This year's highlights:
- The museum's former sawmill exhibition was revamped with the title The Forest, the Saw and the Machines.
- The website experienced significant growth in 2025, with a total of 689,000 unique visits, corresponding to an increase of 59.5 percent compared to 2024.
- On March 18 and 19, the museum organized free science days for grades 5–7 in collaboration with Tekna. Approximately 1,200 students participated in activities in artificial intelligence, biology, physics, and rocket launching.
- During the Easter holidays, the museum organized the Easter Mystery, in which the robotic seal Paro was “stolen.” Visitors participated in the investigation through activities such as fingerprint analysis, UV reading of secret messages, and microscope examinations.
- In April, 150 student teachers from OsloMet participated in the event Sustainability and Entrepreneurship, a collaboration between the museum, OsloMet, the UN and Young Entrepreneurship.
- In the summer of 2025, the National Medical Museum contributed to the exhibition Lifeblood - Edvard Munch, which was shown at the Munch Museum.
- During the fall break, the museum organized the program Robotene kommer. The public could experience robots and technology through various activities for the whole family, including demonstrations of a pancake robot and a robot drawing show with Flu Hartberg.
- Research Square was also organized in 2025 in collaboration with the Faculty of Medicine and the Department of Pharmacy at UiO. Schoolchildren and families were able to meet researchers and explore the body through VR experiences, learning about brain and heart research, diet, organ donation and groundbreaking cancer treatment, among other things.
- On October 11, the museum got a waterwheel back in motion. The new waterwheel was built with a focus on locally sourced materials and traditional construction methods, with support from Sparebankstiftelsen DNB and Statkraft.
- On October 25th and 26th, the Women's Health Festival, Norway's first of its kind, was organized with themes including heart health, prenatal care, menopause, endometriosis and abortion.
- On December 4, the temporary exhibition Work Photography/Photowork, inviting the public to explore how photography documents and shapes narratives about working life.
- By the end of 2025, the museum had had 245,743 visitors. This is the highest number of visitors since the pandemic and reflects broad public support for the museum's exhibitions, school programs, and weekend and holiday activities.
- 500 school classes participated in educational programs at Oslo Science Centre . This is a record.
- For the first time, the museum, together with Åpent Bakeri, has organized Oslo's most fun gingerbread town. A new tradition has now begun.